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Implementing Genetic Addiction Risk Screening for Improved Child Outcomes

Implementing Genetic Addiction Risk Screening for Improved Child Outcomes

Introduction

The opioid and psychostimulant epidemic in the United States continues to pose significant public health challenges. Recent research, such as the study titled "Americas’ opioid/psychostimulant epidemic would benefit from general population early identification of genetic addiction risk especially in children of alcoholics (COAs)" by Blum et al. (2020), underscores the importance of early identification of genetic addiction risks. This blog explores how practitioners can leverage these findings to improve outcomes for children, particularly those with a family history of alcoholism.

Understanding the Epidemic

According to the CDC, more than 700,000 people died from drug overdoses between 1999 and 2017, with opioids being a significant contributor. The economic burden of opioid misuse is estimated at $78.5 billion annually. These statistics highlight the urgent need for effective prevention and intervention strategies.

The Role of Genetic Screening

The research by Blum et al. emphasizes the potential benefits of early genetic screening, particularly for children of alcoholics (COAs). Genetic Addiction Risk Score (GARS) testing can identify children at higher risk for developing substance use disorders (SUDs). This proactive approach can help mitigate the long-term impacts of addiction.

Key Findings

The study found that children with the DRD2 A1 allele, a genetic marker associated with Reward Deficiency Syndrome (RDS), are at a higher risk for developing addictive behaviors. This finding is particularly relevant for COAs, who are four times more likely to become alcoholics compared to the general population.

Implementing Genetic Screening in Practice

Practitioners can integrate genetic screening into their practice to identify at-risk children early. Here are some steps to consider:

Encouraging Further Research

While the current research provides valuable insights, more studies are needed to fully understand the implications of genetic addiction risk screening. Practitioners are encouraged to participate in or support ongoing research efforts to refine these strategies further.

Conclusion

Early identification of genetic addiction risks can significantly improve outcomes for children, especially those with a family history of alcoholism. By integrating genetic screening into their practice, practitioners can provide more effective, personalized interventions. To read the original research paper, please follow this link: Americas’ opioid/psychostimulant epidemic would benefit from general population early identification of genetic addiction risk especially in children of alcoholics (COAs).


Citation: Blum, K., Baron, D., Hauser, M., Henriksen, S., Thanos, P. K., Black, C., Siwicki, D., Modestino, E. J., Downs, B. W., Badgaiyan, S., Simpatico, T. A., Boyett, B., & Badgaiyan, R. D. (2020). Americas’ opioid/psychostimulant epidemic would benefit from general population early identification of genetic addiction risk especially in children of alcoholics (COAs). Journal of Systems and Integrative Neuroscience, PMC7032561. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7032561/?report=classic
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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