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Unbelievable Breakthrough in Neonatal Diabetes: What Every Practitioner Needs to Know!

Unbelievable Breakthrough in Neonatal Diabetes: What Every Practitioner Needs to Know!

Unlocking the Potential of Sulfonylureas in Neonatal Diabetes

As practitioners dedicated to improving outcomes for children, staying abreast of the latest research is crucial. A groundbreaking study published in The Lancet Diabetes & Endocrinology sheds light on the long-term effectiveness and safety of sulfonylureas in treating neonatal diabetes due to KCNJ11 mutations. This international cohort study provides compelling evidence that could transform treatment protocols and improve patient outcomes significantly.

Key Findings from the Study

The study followed 81 patients over a median period of 10.2 years. Here are some pivotal findings:

Implications for Practice

This study provides robust evidence that sulfonylureas are not only effective but also safe for long-term use in patients with KCNJ11 permanent neonatal diabetes. Here’s how practitioners can leverage these findings:

Encouraging Further Research

While the study provides substantial insights, it also opens avenues for further research:

For practitioners committed to data-driven decisions, these findings offer a compelling case for integrating sulfonylureas into the treatment regimen for neonatal diabetes due to KCNJ11 mutations. By doing so, we can enhance the quality of life for our young patients and their families.

To read the original research paper, please follow this link: Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study.


Citation: Bowman, P., Sulen, Å., Barbetti, F., Beltrand, J., Svalastoga, P., Codner, E., Tessmann, E. H., Juliusson, P. B., Skrivarhaug, T., Pearson, E. R., Flanagan, S. E., Babiker, T., Thomas, N. J., Shepherd, M. H., Ellard, S., Klimes, I., Szopa, M., Polak, M., Iafusco, D., & Hattersley, A. T. (2018). Effectiveness and safety of long-term treatment with sulfonylureas in patients with neonatal diabetes due to KCNJ11 mutations: an international cohort study. The Lancet Diabetes & Endocrinology. https://doi.org/10.1016/S2213-8587(18)30106-2
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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