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Understanding Acute Topiramate Toxicity in Children: Key Insights for Practitioners

Understanding Acute Topiramate Toxicity in Children: Key Insights for Practitioners

Introduction

In the realm of pediatric care, understanding the potential risks and side effects of medications is crucial for practitioners. One such medication is Topiramate, an anti-epileptic drug commonly used to treat seizures and migraines. However, its off-label use has been on the rise, leading to unforeseen consequences, particularly in children. The research article titled "Acute Topiramate Toxicity in a Five-Year-Old Child" offers valuable insights into such a case, providing an opportunity for practitioners to enhance their skills and knowledge in managing similar situations.

Case Overview

The case study revolves around a five-year-old boy who presented with symptoms of acute encephalopathy, including lethargy, slurred speech, hallucinations, and agitation. Despite normal results from various diagnostic tests, a saliva toxicology screen revealed a high level of Topiramate, which the child had not been prescribed. It was later discovered that the mother was using Topiramate for weight loss, highlighting the potential for accidental exposure in children.

Key Takeaways for Practitioners

From this case, practitioners can derive several important lessons:

Implications for Online Therapy Providers

As providers of online therapy services, it is essential to integrate these insights into practice. Here are some strategies to consider:

Encouraging Further Research

This case underscores the need for further research into the effects of off-label drug use in children. Practitioners are encouraged to explore this area, contributing to a broader understanding of drug safety and efficacy in pediatric populations.

To read the original research paper, please follow this link: Acute Topiramate Toxicity in a Five-Year-Old Child.


Citation: Muacevic, A., Adler, J. R., Baidoun, M., & Elgendy, M. (2021). Acute Topiramate Toxicity in a Five-Year-Old Child. Cureus, 13(3), e13747. https://doi.org/10.7759/cureus.13747
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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