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Unlocking Alzheimer's: How Genetic Discoveries Can Enhance Your Practice

Unlocking Alzheimer\'s: How Genetic Discoveries Can Enhance Your Practice

As a practitioner in the field of special education or therapy services, staying informed about the latest research in related fields can significantly enhance your practice. One such area of interest is the recent advances in genetic research on Alzheimer's disease (AD), particularly the use of polygenic risk scores (PRS) for risk stratification.

The Power of Polygenic Risk Scores

The study titled Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores offers groundbreaking insights into how genetic variants can predict the onset and progression of AD. The research conducted a large-scale genome-wide meta-analysis involving over 400,000 individuals, identifying six new genetic loci associated with AD risk.

Polygenic risk scores aggregate the effects of multiple genetic variants to estimate an individual's predisposition to developing AD. This tool has shown potential in identifying individuals at high genetic risk, allowing for earlier intervention strategies and personalized treatment plans.

Implementing Research Outcomes in Practice

For practitioners providing therapy services, understanding and utilizing PRS can be transformative. Here's how you can implement these findings:

Encouraging Further Research

The findings from this study also highlight areas where further research is needed. Encouraging collaboration between schools, researchers, and healthcare providers can foster a deeper understanding of how genetic factors influence cognitive health. Consider partnering with research institutions to contribute data or participate in studies that aim to refine PRS tools.

The Future of Therapy Services

The integration of genetic discoveries into therapeutic practices is an exciting frontier that promises more personalized and effective interventions. By staying informed and proactive, practitioners can play a crucial role in advancing the field of special education and therapy services.

To read the original research paper, please follow this link: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores.


Citation: de Rojas, I., Moreno-Grau, S., Tesi, N., Grenier-Boley, B., Andrade, V., Jansen, I. E., ... & Ruiz, A. (2021). Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores. Nature Communications, 12(3417). https://doi.org/10.1038/s41467-021-22491-8
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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