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Implications of Brain Volume Research on Chronic Ketamine Users for Speech-Language Pathologists

Implications of Brain Volume Research on Chronic Ketamine Users for Speech-Language Pathologists

Understanding Brain Volume Changes in Chronic Ketamine Users: Insights for Speech-Language Pathologists

As speech-language pathologists (SLPs), understanding the neurological underpinnings of communication disorders is crucial for developing effective therapeutic interventions. A recent study titled Brain volume in chronic ketamine users — relationship to sub-threshold psychotic symptoms and relevance to schizophrenia provides valuable insights into how chronic ketamine use impacts brain volume, which may have implications for our practice.

Key Findings of the Study

The study investigated the effects of chronic ketamine use on brain volume and its association with sub-threshold psychotic symptoms. The researchers found that chronic ketamine users had significantly lower grey matter volumes in several brain regions, including the nucleus accumbens, caudate nucleus, cerebellum, and total cortex. These findings suggest that chronic ketamine use may lead to structural brain changes similar to those observed in schizophrenia.

Interestingly, the study also noted that while ketamine users exhibited higher sub-threshold psychotic symptoms, these symptoms did not correlate directly with the observed brain volume reductions. This indicates that the mechanisms underlying these symptoms and structural changes may be distinct.

Implications for Speech-Language Pathology

Understanding the relationship between brain structure and function is essential for SLPs, especially when working with populations that may be affected by substance use or neurodevelopmental disorders. Here are some ways this research can inform our practice:

Encouraging Further Exploration

The findings from this study underscore the importance of ongoing research into the brain-behavior relationship. For practitioners, staying informed about the latest research can enhance clinical practice and improve outcomes for clients. Consider exploring additional studies on brain volume and communication disorders to deepen your understanding and refine your therapeutic approaches.

To read the original research paper, please follow this link: Brain volume in chronic ketamine users — relationship to sub-threshold psychotic symptoms and relevance to schizophrenia.


Citation: Chesters, R. A., Pepper, F., Morgan, C., Cooper, J. D., Howes, O. D., Vernon, A. C., & Stone, J. M. (2021). Brain volume in chronic ketamine users — relationship to sub-threshold psychotic symptoms and relevance to schizophrenia. Psychopharmacology (Berl). https://doi.org/10.1007/s00213-021-05873-0
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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