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Photostimulation of Brain Lymphatics: A Novel Approach to Treating Intraventricular Hemorrhage in Newborns

Photostimulation of Brain Lymphatics: A Novel Approach to Treating Intraventricular Hemorrhage in Newborns

Introduction

Intraventricular hemorrhage (IVH) is a severe brain injury often seen in premature infants, with limited treatment options available. The recent study titled "Photostimulation of brain lymphatics in male newborn and adult rodents for therapy of intraventricular hemorrhage" by Li et al. (2023) presents promising findings that could revolutionize the treatment of IVH through non-invasive photostimulation techniques. This blog aims to translate these findings into actionable insights for practitioners working with children, particularly those providing online therapy services through platforms like TinyEYE.

Key Findings from the Research

The study conducted by Li et al. (2023) demonstrated that transcranial photostimulation can significantly enhance the clearance of red blood cells (RBCs) from the brain's ventricular system in both newborn and adult rodents. The researchers found that photostimulation at a wavelength of 1267 nm improved the function of meningeal lymphatic vessels (MLVs), which are crucial for draining RBCs from the brain into the deep cervical lymph nodes (dcLNs). This process was shown to expedite recovery and improve neurological outcomes in rodents with IVH.

Clinical Implications for Practitioners

For practitioners working with children, especially those in school settings, the implications of these findings are profound. Here are some key takeaways and potential applications:

Encouraging Further Research

While the findings are promising, further research is essential to validate the efficacy and safety of photostimulation in human infants. Practitioners are encouraged to stay updated with ongoing clinical trials and contribute to research efforts where possible. Collaborative research can help refine the protocols and establish standardized guidelines for the use of photostimulation in treating IVH.

Conclusion

The study by Li et al. (2023) opens up new avenues for treating intraventricular hemorrhage in newborns through non-invasive photostimulation. For practitioners dedicated to improving outcomes for children, integrating these findings into practice could significantly enhance the quality of care. By staying informed and contributing to further research, we can collectively advance the field and provide better therapeutic options for vulnerable infants.

To read the original research paper, please follow this link: Photostimulation of brain lymphatics in male newborn and adult rodents for therapy of intraventricular hemorrhage.


Citation: Li, D., Liu, S., Yu, T., Liu, Z., Sun, S., Bragin, D., Shirokov, A., Navolokin, N., Bragina, O., Hu, Z., Kurths, J., Fedosov, I., Blokhina, I., Dubrovski, A., Khorovodov, A., Terskov, A., Tzoy, M., Semyachkina-Glushkovskaya, O., & Zhu, D. (2023). Photostimulation of brain lymphatics in male newborn and adult rodents for therapy of intraventricular hemorrhage. Nature Communications, 14, 6104. https://doi.org/10.1038/s41467-023-41710-y
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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Apply Today

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in online therapy apply today!

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