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Understanding Biomarker Results: A Guide for Practitioners

Understanding Biomarker Results: A Guide for Practitioners

In the ever-evolving field of environmental health research, practitioners are often faced with the challenge of communicating complex and unexpected findings to study participants. The research article "Sharing Unexpected Biomarker Results with Study Participants" provides valuable insights into this process, particularly in the context of environmental exposures and biomarker studies involving children.

The Importance of Communication in Research

Effective communication is crucial in research, especially when dealing with unexpected results that may have significant implications for participants. The study highlighted in the article involved elevated levels of perfluorooctanoate (PFOA) found in young girls from a specific community. This finding posed ethical dilemmas and required careful consideration of how to inform participants and their families.

Developing a Communication Plan

A well-developed communication plan is essential for researchers when unexpected results arise. The research team in the study created a comprehensive strategy that included:

This approach ensured that the information was conveyed clearly and consistently, addressing potential questions and concerns from participants.

Ethical Considerations in Reporting Results

The ethical considerations surrounding the reporting of unexpected biomarker results are multifaceted. The precautionary principle played a significant role in guiding the research team's decision-making process. This principle advocates for protecting human health even when risks are uncertain, emphasizing the responsibility to inform participants about potential exposures.

The right-to-know regulations further supported the decision to disclose findings to participants. These regulations underscore the importance of transparency and respect for individuals' rights to be informed about environmental risks they may face.

Navigating Challenges and Concerns

The research team faced several challenges in deciding to report the PFOA findings. Concerns included potential impacts on study recruitment, ongoing litigation related to PFOA contamination, and the time-consuming nature of accurately reporting results. Despite these challenges, the team prioritized ethical obligations and participant rights.

Lessons Learned for Practitioners

The experiences shared in the research article offer valuable lessons for practitioners looking to improve their skills in communicating complex research findings:

The transdisciplinary approach adopted by the research team exemplifies how diverse expertise can lead to effective solutions that benefit both researchers and participants. Practitioners can apply these insights to enhance their own practices and ensure ethical standards are maintained.

To read the original research paper, please follow this link: Sharing Unexpected Biomarker Results with Study Participants.


Citation: Hernick, A. D., Brown, M. K., Pinney, S. M., Biro, F. M., Ball, K. M., & Bornschein, R. L. (2011). Sharing unexpected biomarker results with study participants. Environmental Health Perspectives, 119(1), 1-5.
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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