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Understanding the Anterior Globus Pallidus Externus: Implications for Practitioners

Understanding the Anterior Globus Pallidus Externus: Implications for Practitioners

Introduction

The basal ganglia, a group of nuclei in the brain, have long been associated with motor control. However, recent research has expanded our understanding of their functions to include cognitive, emotional, and associative roles. A pivotal study titled "The Anterior Globus Pallidus Externus of Basal Ganglia as Primarily a Limbic and Associative Territory" sheds light on the specific functions of the globus pallidus externus (GPe), particularly its anterior region. This blog explores the implications of these findings for practitioners, especially those in the field of speech-language pathology.

Key Findings

The study highlights that the anterior region of the GPe is primarily associated with limbic and associative functions, rather than motor control. This was evidenced by a case study of a young man with cognitive, perceptual, and mood disturbances, but no significant motor symptoms. Brain imaging revealed dense calcifications in the anterior GPe, suggesting a link between this region and non-motor symptoms.

Implications for Practitioners

For practitioners, these findings emphasize the importance of considering the basal ganglia's non-motor functions when assessing and treating patients. Here are some practical takeaways:

Encouraging Further Research

The study underscores the need for more human-based research to validate findings from animal studies. Practitioners can contribute to this body of knowledge by documenting clinical observations and participating in collaborative research efforts.

To read the original research paper, please follow this link: The Anterior Globus Pallidus Externus of Basal Ganglia as Primarily a Limbic and Associative Territory.


Citation: Muacevic, A., Adler, J. R., Saad, P., Shendrik, K. S., Karroum, P. J., Azizi, H., & Jolayemi, A. (2020). The anterior globus pallidus externus of basal ganglia as primarily a limbic and associative territory. Cureus, 12(12), e11846. https://doi.org/10.7759/cureus.11846
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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